Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population.
Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder characterized by motor and vocal tics.Hyperactivity of dopaminergic transmission is considered a prime abnormality in the pathophysiology of tics.There are reciprocal antagonistic interactions between adenosine and dopamine transmission.The aim of the study was to analyze the ass